To Spider-Man's chagrin, Cordco's satellite launches into the stratosphere with Doc Ock's deadly poison onboard! Oh no, does this mean the Earth is doomed? Not exactly. Because the six-armed doctor's poison is actually just a cure for cocaine addiction! Otto Octavius' master plan is simply to extort rich addicts who have to keep using! But the poison has the side effect of destroying the ozone layer! And only Peter Parker and his labmates at ESU can save the planet now! Meanwhile at the TV studio across town, Mary Jane finds herself in a smaller scale life and death struggle vs. Jonathan Caesar! And only one of them will survive!
